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Method and apparatus for measuring immunological reaction with the aid of fluctuation in intensity of scattered light
其他题名Method and apparatus for measuring immunological reaction with the aid of fluctuation in intensity of scattered light
NAMBA, AKIHIRO; UCHINO, FUMIO; TATEOKA, HITOSHI; OHNO, MASAHIRO; ANDO, OUTARO; KARAKI, KOUICHI; NAGASAKI, TATSUO
1988-08-09
专利权人OLYMPUS OPTICAL CO., LTD.
公开日期1988-08-09
授权国家美国
专利类型授权发明
摘要A coherent laser light flux is projected into a cell made of transparent quartz and light scattered from particles suspended in an antigen-antibody reaction liquid contained in the cell is detected by a photomultiplier by means of a collimator. An output electrical signal from the photomultiplier is sampled at different time instances and samplings are supplied to a fast Fourier transformer to derive a plurality of power spectrum densities of fluctuation in intensity of the scattered light. A plurality of power spectrum densities are averaged to generate a mean power spectrum density. An amount of antigen contained in the reaction liquid is measured in accordance with the mean power spectrum density.
其他摘要将相干激光光束投射到由透明石英制成的单元中,并且通过光电倍增器通过准直器检测从悬浮在​​细胞中包含的抗原 - 抗体反应液中的颗粒散射的光。来自光电倍增器的输出电信号在不同的时刻被采样,并且采样被提供给快速傅里叶变换器,以导出散射光强度波动的多个功率谱密度。平均多个功率谱密度以产生平均功率谱密度。根据平均功率谱密度测量反应液中含有的抗原量。
申请日期1985-08-27
专利号US4762413
专利状态失效
申请号US06/769965
公开(公告)号US4762413
IPC 分类号G01N33/53 | G01N21/51 | G01N21/25 | G01N21/47 | G01N15/02 | G01N35/00 | G01J3/44 | G01N21/03 | G01N21/59 | G01N33/557 | G01N35/02
专利代理人-
代理机构PARKHURST & OLIFF
文献类型专利
条目标识符http://ir.opt.ac.cn/handle/181661/34401
专题半导体激光器专利数据库
作者单位OLYMPUS OPTICAL CO., LTD.
推荐引用方式
GB/T 7714
NAMBA, AKIHIRO,UCHINO, FUMIO,TATEOKA, HITOSHI,et al. Method and apparatus for measuring immunological reaction with the aid of fluctuation in intensity of scattered light. US4762413[P]. 1988-08-09.
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