Portable laser and process for pain research

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	Portable laser and process for pain research
其他题名	Portable laser and process for pain research
	NEMENOV, MIKHALL
	2011-10-04
专利权人	NEMENOV MIKHALL
公开日期	2011-10-04
授权国家	美国
专利类型	授权发明
摘要	A process and laser system for in vitro and in vivo pain research, pain clinical testing and pain management. In preferred embodiments of the present invention a diode laser operating at a 980 nm wavelength is used to produce warmth, tickling, itching, touch, burning, hot pain or pin-prick pain. The device and methods can be used for stimulation of a single nerve fiber, groups of nerve fibers, nerve fibers of single type only as well as more the one type of nerve fibers simultaneously. The present invention is especially useful for research of human/animal sensitivity, pain management, drug investigation and testing, and psychophysiology/electrophysiology studies. The device and methods permit non-contact, reproducible and controlled tests that avoid risk of skin damage. Applicant an his fellow workers have shown that tests with human subjects with the process and laser of the present invention correlate perfectly with laboratory tests with nerve fibers of rats. The device and the methods can be applied in a wide variety of situations involving the study and treatment of pain. Preferred embodiments of the present invention provide laser systems and techniques that permit mapping and single mode activation of C fibers and A-delta fibers.
其他摘要	用于体外和体内疼痛研究，疼痛临床测试和疼痛管理的过程和激光系统。在本发明的优选实施例中，使用在980nm波长下操作的二极管激光器来产生温暖，搔痒，瘙痒，触摸，灼热，热痛或针刺疼痛。该装置和方法可以用于刺激单个神经纤维，神经纤维组，单一类型的神经纤维以及同时更多的一种类型的神经纤维。本发明特别适用于人/动物敏感性，疼痛管理，药物研究和测试以及心理生理学/电生理学研究的研究。该装置和方法允许非接触，可再现和受控的测试，以避免皮肤损伤的风险。申请人和他的同事已经表明，使用本发明的方法和激光的人类受试者的测试与用大鼠的神经纤维的实验室测试完全相关。该装置和方法可以应用于涉及疼痛研究和治疗的各种情况。本发明的优选实施例提供了允许C光纤和A-δ光纤的映射和单模激活的激光系统和技术。
申请日期	2008-01-29
专利号	US8029553
专利状态	授权
申请号	US12/011794
公开（公告）号	US8029553
IPC 分类号	A61B18/20
专利代理人	-
代理机构	ROSS, JOHN R. ROSS,III, JOHN R.
文献类型	专利
条目标识符	http://ir.opt.ac.cn/handle/181661/32690
专题	半导体激光器专利数据库
作者单位	NEMENOV MIKHALL
推荐引用方式 GB/T 7714	NEMENOV, MIKHALL. Portable laser and process for pain research. US8029553[P]. 2011-10-04.

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