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Aberration correction method based on double-helix point spread function
Wang, Zhaojun1,2; Cai, Yanan1,2; Liang, Yansheng1,2; Dan, Dan1,3; Yao, Baoli1,3; Lei, Ming1,3
作者部门瞬态光学技术国家重点实验室
2019-03-01
发表期刊Journal of Biomedical Optics
ISSN10833668;15602281
卷号24期号:3
产权排序1
摘要Point spread function (PSF) engineering has met with lots of interest in various optical imaging techniques, including super-resolution microscopy, microparticle tracking, and extended depth-of-field microscopy. The intensity distributions of the modified PSFs often suffer from deteriorations caused by system aberrations, which greatly degrade the image contrast, resolution, or localization precision. We present an aberration correction method using a spiral-phase-based double-helix PSF as an aberration indicator, which is sensitive and quantitatively correlated to the spherical aberration, coma, and astigmatism. Superior to the routine iteration-based correction methods, the presented approach is iteration-free and the aberration coefficients can be directly calculated with the measured parameters, relieving the computing burden. The validity of the method is verified by both examining the intensity distribution of the conventional Gaussian PSF in three dimensions and observing muntjac skin fibroblast cells. This iteration-free correction method has a potential application in PSF engineering systems equipped with a spatial light modulator. ? 2018 Society of Photo-Optical Instrumentation Engineers (SPIE).
DOI10.1117/1.JBO.24.3.031005
收录类别EI
语种英语
出版者SPIE
EI入藏号20183805826511
引用统计
文献类型期刊论文
条目标识符http://ir.opt.ac.cn/handle/181661/30631
专题瞬态光学技术国家重点实验室
通讯作者Lei, Ming
作者单位1.Chinese Academy of Sciences, Xi'an Institute of Optics and Precision Mechanics, State Key Laboratory of Transient Optics and Photonics, No. 17 Xinxi Road, Xi'an, Shaanxi; 710119, China;
2.University of Chinese Academy of Sciences, No. 19 Yuquan Road, Shijingshan District Beijing; 100049, China;
3.Xi'an Jiaotong University, No. 28 Xianning West Road, Xi'an, Shaanxi; 710049, China
推荐引用方式
GB/T 7714
Wang, Zhaojun,Cai, Yanan,Liang, Yansheng,et al. Aberration correction method based on double-helix point spread function[J]. Journal of Biomedical Optics,2019,24(3).
APA Wang, Zhaojun,Cai, Yanan,Liang, Yansheng,Dan, Dan,Yao, Baoli,&Lei, Ming.(2019).Aberration correction method based on double-helix point spread function.Journal of Biomedical Optics,24(3).
MLA Wang, Zhaojun,et al."Aberration correction method based on double-helix point spread function".Journal of Biomedical Optics 24.3(2019).
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