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Sensitive label-free hemoglobin detection based on polydopamine functionalized graphene oxide coated micro-tapered long-period fiber grating
Li, Yansong1,2; Du, Mengyu1,2; He, Shuxuan1,2; Wang, Ruiduo3; Zhang, Zaikun3; Wang, Qiang1,2
作者部门先进光电与生物材料研究室
2023-03
发表期刊OPTIK
ISSN0030-4026;1618-1336
卷号275
产权排序3
摘要

The GO and PDA-GO functionalized TLPG based sensitive and label-free optical biosensor for human hemoglobin detection was demonstrated. The PDA-GO and GO were separately deposited onto fiber surface, the deposited materials provide a large number of binding sites to adsorb the hemoglobin and can further change the RI of fiber surface, and can provide more binding sites owing to the large specific surface area, and it exhibits higher sensing sensitivity of 3.14 mg/mL and the LOD can reach 0.057 mg/mL. In addition, the sensing was carried out in the presence of inference compounds and also proved its ideal reusability. The usage of PDA-GO as a bio-interface layer enables strong interference of optical waves as well as excellent biocompatibility, which is considered to be valuable for biosensing applications.

关键词Biosensor Tapered long -period fiber grating Graphene oxide Polydopamine Hemoglobin
DOI10.1016/j.ijleo.2023.170626
收录类别SCI
语种英语
WOS记录号WOS:000963884600001
出版者ELSEVIER GMBH
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.opt.ac.cn/handle/181661/96420
专题光子功能材料与器件研究室
通讯作者Wang, Ruiduo; Wang, Qiang
作者单位1.Xi An Jiao Tong Univ, Dept Anesthesiol, Xian 710061, Shaanxi, Peoples R China
2.Xi An Jiao Tong Univ, Affiliated Hosp 1, Ctr Brain Sci, Xian 710061, Shaanxi, Peoples R China
3.Chinese Acad Sci, Xian Inst Opt & Precis Mech, State Key Lab Transient Opt & Photon, Xian 710119, Peoples R China
推荐引用方式
GB/T 7714
Li, Yansong,Du, Mengyu,He, Shuxuan,et al. Sensitive label-free hemoglobin detection based on polydopamine functionalized graphene oxide coated micro-tapered long-period fiber grating[J]. OPTIK,2023,275.
APA Li, Yansong,Du, Mengyu,He, Shuxuan,Wang, Ruiduo,Zhang, Zaikun,&Wang, Qiang.(2023).Sensitive label-free hemoglobin detection based on polydopamine functionalized graphene oxide coated micro-tapered long-period fiber grating.OPTIK,275.
MLA Li, Yansong,et al."Sensitive label-free hemoglobin detection based on polydopamine functionalized graphene oxide coated micro-tapered long-period fiber grating".OPTIK 275(2023).
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