System and method for molecule sensing using evanescent light coupling approach

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	System and method for molecule sensing using evanescent light coupling approach
其他题名	System and method for molecule sensing using evanescent light coupling approach
	LU, TAO
	2017-11-16
专利权人	UVIC INDUSTRY PARTNERSHIPS INC.
公开日期	2017-11-16
授权国家	美国
专利类型	发明申请
摘要	A system and a method for optical sensing of single molecule or molecules in various concentrations are provided. The optical sensor system comprises a first fiber, a second fiber, a light source and a detection device. The first fiber and the second fiber are fused together to form an optical coupler. The first fiber serves as the passageway for the analyte, while the second fiber serves as the waveguide for the light that will interact with the said analyte. One end of the second fiber is connected to the light source (e.g. laser), and the opposite end is connected to the detection device (e.g. spectrometer). The analyte is introduced into the first fiber through one of its ends, and is allowed to flow through inside the hollow core of the said first fiber. When light is delivered through the input end of the second fiber, the evanescent light is formed in the optical coupler and is allowed to interact with the analyte in the first fiber. One scenario in this analyte-light interaction results in, for example, the generation of Raman emission that is used as the probing signal. The spectrum of the Raman emission is analyzed by the detection device to determine the presence of target molecule.
其他摘要	提供了用于光学感测各种浓度的单个分子或分子的系统和方法。光学传感器系统包括第一光纤，第二光纤，光源和检测装置。第一光纤和第二光纤熔合在一起以形成光耦合器。第一纤维用作分析物的通道，而第二纤维用作将与所述分析物相互作用的光的波导。第二光纤的一端连接到光源（例如激光器），而另一端连接到检测装置（例如光谱仪）。分析物通过其一端引入第一纤维中，并允许其流过所述第一纤维的中空芯内部。当光通过第二光纤的输入端传送时，瞬逝光在光耦合器中形成并且允许与第一光纤中的分析物相互作用。该分析物 - 光相互作用中的一种情况导致例如产生用作探测信号的拉曼发射。通过检测装置分析拉曼发射的光谱以确定靶分子的存在。
主权项	An apparatus, comprising: a fiber defining an analyte passageway situated to receive an analyte having a measurable optical characteristic; an optical waveguide including an input end separate from the analyte passageway and further including a waveguide portion optically evanescently coupled to a passageway portion of the analyte passageway so as to form an analyte detection region; a light source optically coupled to the input end of the optical waveguide so as to direct a detection beam through the optical waveguide to the analyte detection region to form an analyte response beam associated with the measurable optical characteristic; and an optical detector optically coupled to the optical waveguide so as to receive the analyte response beam from the analyte detection region through the optical waveguide.
申请日期	2017-01-27
专利号	US20170328836A1
专利状态	授权
申请号	US15/418350
公开（公告）号	US20170328836A1
IPC 分类号	G01N21/65 \| G02B6/032 \| G02B6/255
专利代理人	-
代理机构	-
文献类型	专利
条目标识符	http://ir.opt.ac.cn/handle/181661/54761
专题	半导体激光器专利数据库
作者单位	UVIC INDUSTRY PARTNERSHIPS INC.
推荐引用方式 GB/T 7714	LU, TAO. System and method for molecule sensing using evanescent light coupling approach. US20170328836A1[P]. 2017-11-16.