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Optical system for cell imaging
其他题名Optical system for cell imaging
LAUDO JOHN S.; WELLER ALBERT E. III; GRIMES STEVE L.; HAUBERT THOMAS D.; NAVIN ERIC R.
2006-06-01
专利权人BATTELLE MEMORIAL INSTITUTE
公开日期2006-06-01
授权国家加拿大
专利类型发明申请
摘要A microscope system (10, 10~, 10~~, 10~~~)includes a laser (18) or light emitting diode (18~~~) that generates source light having a non-uniform spatial distribution. An optical system includes an objective (40) defining a field of view, and an optical train (22, 22~, 22~~, 22~~~) configured to convert the source light into an enlarged-diameter collimated light, to spatially homogenize the enlarged-diameter collimated light, and to couple the homogenized enlarged-diameter collimated light into the objective to provide substantially uniform static illumination of the field of view. A camera system (56) is statically optically coupled by the objective with at least most of the field of view.
其他摘要显微镜系统(10,10,10,10~10)包括激光器(18)或发光二极管(18~),其产生具有不均匀空间分布的源光。一种光学系统,包括:物镜(40),其限定视场;以及光学系统(22,22~,22~,22~),被配置为将源光转换为放大直径的准直光,在空间上均匀化扩大直径的准直光,并将均匀化的放大直径准直光耦合到物镜中,以提供视场的基本均匀的静态照明。相机系统(56)通过物镜静态光学耦合至少大部分视场。
主权项An optical system for imaging a microscope field of view, the optical system comprising: an objective focused on the microscope field of view; and an optical train including one or more stationary optical components configured to receive a small diameter laser beam having a non-uniform spatial distribution and to output a corrected spatial distribution to the objective that when focused by the objective at the microscope field of view provides substantially uniform static illumination over substantially the entire microscope field of view, the optical train including: a large-area stationary optical component that improves spatial uniformity of collimated light having a diameter substantially larger than the diameter of the small diameter laser beam, a stationary beam expander disposed before the large- area stationary optical component in the optical train, the stationary beam expander expanding the small diameter laser beam to produce collimated light having a substantially larger diameter suitable for coupling into the large-area stationary optical component, and a stationary beam reducer disposed after the large- area stationary optical component in the optical train, the stationary beam reducer coupling the collimated light into the objective.
申请日期2005-10-27
专利号CA2588126A1
专利状态失效
申请号CA2588126
公开(公告)号CA2588126A1
IPC 分类号G02B27/09 | B01L3/00 | B01L9/06 | G01N15/04 | G01N33/50 | G02B21/08
专利代理人FETHERSTONHAUGH & CO.
代理机构FETHERSTONHAUGH & CO.
文献类型专利
条目标识符http://ir.opt.ac.cn/handle/181661/53741
专题半导体激光器专利数据库
作者单位BATTELLE MEMORIAL INSTITUTE
推荐引用方式
GB/T 7714
LAUDO JOHN S.,WELLER ALBERT E. III,GRIMES STEVE L.,et al. Optical system for cell imaging. CA2588126A1[P]. 2006-06-01.
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