| Segmentation of White Blood Cell from Acute Lymphoblastic Leukemia Images Using Dual-Threshold Method | |
| Li, Yan1,2; Zhu, Rui1; Mi, Lei1; Cao, Yihui1,2; Yao, Di3 | |
| 作者部门 | 瞬态光学技术国家重点实验室 |
| 2016 | |
| 发表期刊 | COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE
 |
| ISSN | 1748-670X |
| 产权排序 | 1 |
| 摘要 | We propose a dual-threshold method based on a strategic combination of RGB and HSV color space for white blood cell (WBC) segmentation. The proposed method consists of three main parts: preprocessing, threshold segmentation, and postprocessing. In the preprocessing part, we get two images for further processing: one contrast-stretched gray image and one H component image from transformed HSV color space. In the threshold segmentation part, a dual-threshold method is proposed for improving the conventional single-threshold approaches and a golden section search method is used for determining the optimal thresholds. For the postprocessing part, mathematical morphology and median filtering are utilized to denoise and remove incomplete WBCs. The proposed method was tested in segmenting the lymphoblasts on a public Acute Lymphoblastic Leukemia (ALL) image dataset. The results show that the performance of the proposed method is better than single-threshold approach independently performed in RGB and HSV color space and the overall single WBC segmentation accuracy reaches 97.85%, showing a good prospect in subsequent lymphoblast classification and ALL diagnosis. |
| 文章类型 | Article |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| DOI | 10.1155/2016/9514707 |
| 收录类别 | SCI |
| 关键词[WOS] | COLOR |
| 语种 | 英语 |
| WOS研究方向 | Mathematical & Computational Biology |
| 项目资助者 | National Key Science and Technology Support Program(2015BA101B06) ; Science and Technology Coordination and Innovation(2013KTCQ03-09) |
| WOS类目 | Mathematical & Computational Biology |
| WOS记录号 | WOS:000377438500001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.opt.ac.cn/handle/181661/28154 |
| 专题 | 瞬态光学研究室 |
| 作者单位 | 1.Chinese Acad Sci, Xian Inst Opt & Precis Mech, State Key Lab Transient Opt & Photon, Xian 710119, Peoples R China 2.Univ Chinese Acad Sci, 52 Sanlihe Rd, Beijing 100864, Peoples R China 3.Shenzhen Vivolight Med Device & Technol Co Ltd, Shenzhen 518000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Yan,Zhu, Rui,Mi, Lei,et al. Segmentation of White Blood Cell from Acute Lymphoblastic Leukemia Images Using Dual-Threshold Method[J]. COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE,2016. |
| APA | Li, Yan,Zhu, Rui,Mi, Lei,Cao, Yihui,&Yao, Di.(2016).Segmentation of White Blood Cell from Acute Lymphoblastic Leukemia Images Using Dual-Threshold Method.COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE. |
| MLA | Li, Yan,et al."Segmentation of White Blood Cell from Acute Lymphoblastic Leukemia Images Using Dual-Threshold Method".COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2016). |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| Segmentation of Whit（4556KB） | 期刊论文 | 作者接受稿 | 限制开放 | CC BY-NC-SA | 请求全文 | |
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