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Laser irradiation cell photothermal therapy assisted by gold nanoparticles
Yao Cui-Ping; Zhang Zhen-Xi; Yao Bao-Li
作者部门瞬态光学国家重点实验室
2007-03-01
发表期刊PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
ISSN1000-3282
卷号34期号:3页码:312-316
产权排序1
摘要The strong absorption of gold nanoparticles in the visible spectral range allows the localized generation of heat in a volume of only a few tens of nanometer. The efficient conversion of strongly absorbed light by plasmonic gold nanoparticles to heat energy and their easy bioconjugation suggest that the gold nanoparticles can be used as selective photothermal agents in molecular cell targeting. The selective destruction of alkaline phosphatase, the permeabilization of the cell membrane and the selective killing of cells by laser irradiating gold nanoparticles were demonstrated. The potential of using this selective technique in molecularly targeted photothermal therapy and transfection is discussed.
文章类型Article
关键词Laser Irradiation Gold Nanoparticles Biomolecules Cell
WOS标题词Science & Technology ; Life Sciences & Biomedicine
收录类别SCI
关键词[WOS]FEMTOSECOND LASER ; NANOCRYSTALS ; CANCER
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Biophysics
WOS类目Biochemistry & Molecular Biology ; Biophysics
WOS记录号WOS:000245014900013
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.opt.ac.cn/handle/181661/6718
专题瞬态光学研究室
作者单位1.Chinese Acad Sci, State Key Lab Transient Opt & Photon, Xian Inst Opt & Precis Mech, Xian 710119, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
3.Xian Jiaotong Univ, Key Lab Biomed Informat Engn, Minist Educ, Xian 710049, Peoples R China
4.Xian Jiaotong Univ, Inst Biomed Engn, Sch Life Sci & Technol, Xian 710049, Peoples R China
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Yao Cui-Ping,Zhang Zhen-Xi,Yao Bao-Li. Laser irradiation cell photothermal therapy assisted by gold nanoparticles[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2007,34(3):312-316.
APA Yao Cui-Ping,Zhang Zhen-Xi,&Yao Bao-Li.(2007).Laser irradiation cell photothermal therapy assisted by gold nanoparticles.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,34(3),312-316.
MLA Yao Cui-Ping,et al."Laser irradiation cell photothermal therapy assisted by gold nanoparticles".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 34.3(2007):312-316.
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