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Subwavelength resolution Fourier ptychography with hemispherical digital condensers
Pan, An1,2; Zhang, Yan1,2; Wen, Kai3; Zhou, Meiling1,2; Min, Junwei1; Lei, Ming1,4; Yao, Baoli1,4
Source PublicationOPTICS EXPRESS
Contribution Rank1
AbstractFourier ptychography (FP) is a promising computational imaging technique that overcomes the physical space-bandwidth product (SBP) limit of a conventional microscope by applying angular-varied illuminations. However, to date, the effective imaging numerical aperture (NA) achievable with a commercial LED board is still limited to the range of 0.3-0.7 with a 4 x /0.1NA objective due to the geometric constraint with the declined illumination intensities and attenuated signal-to-noise ratio (SNR). Thus the highest achievable half-pitch resolution is usually constrained between 500-1000 nm, which cannot meet the requirements of high-resolution biomedical imaging applications. Although it is possible to improve the resolution by using a high-NA objective lens, the FP approach is less appealing as the decrease of field-of-view (FOV) will far exceed the improvement of spatial resolution in this case. In this paper, we initially present a subwavelength resolution Fourier ptychography (SRFP) platform with a hemispherical digital condenser to provide high-angle programmable plane-wave illuminations of 0.95NA, attaining a 4 x /0.1NA objective with the final effective imaging performance of 1.05NA at a half-pitch resolution of 244 nm with the incident wavelength of 465 nm across a wide FOV of 14.60 mm(2), corresponding to a SBP of 245 megapixels. Our work provides an essential step of FP towards high-throughput imaging applications. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
Indexed BySCI ; EI
WOS IDWOS:000443431400065
EI Accession Number20183605783378
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Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Corresponding AuthorYao, Baoli
Affiliation1.Chinese Acad Sci, State Key Lab Transient Opt & Photon, Xian Inst Opt & Precis Mech, Xian 710119, Shaanxi, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Shaanxi Normal Univ, Coll Phys & Informat Technol, Xian 710071, Shaanxi, Peoples R China
4.Shanxi Univ, Collaborat Innovat Ctr Extreme Opt, Taiyuan 030006, Shanxi, Peoples R China
Recommended Citation
GB/T 7714
Pan, An,Zhang, Yan,Wen, Kai,et al. Subwavelength resolution Fourier ptychography with hemispherical digital condensers[J]. OPTICS EXPRESS,2018,26(18):23119-23131.
APA Pan, An.,Zhang, Yan.,Wen, Kai.,Zhou, Meiling.,Min, Junwei.,...&Yao, Baoli.(2018).Subwavelength resolution Fourier ptychography with hemispherical digital condensers.OPTICS EXPRESS,26(18),23119-23131.
MLA Pan, An,et al."Subwavelength resolution Fourier ptychography with hemispherical digital condensers".OPTICS EXPRESS 26.18(2018):23119-23131.
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